You will benefit from our excellent in-house analytical capabilities for monitoring the bioavailability, disposition and fate of your (radio-labeled) compounds of interest including endogenous metabolites (including various (oxy) lipid, bile acids and endocannabinoid platforms).
We have experience with various animal models (surgical models, knock-out models, disease models), including minipigs (best human GI tract comparison) in various areas from weight management to immune- and brain health.
In collaboration with TNO’s unique Accelerated Mass Spectrometer (AMS) we are able to offer microtracer and mass balance studies, all to understand in detail the fate of your compound in the body.
Typical application areas are bioavailability, bioaccumulation/disposition (Absorption, Distribution, Metabolism and Excretion) studies, Safety and Health claim support studies (efficacy and disposition correlation) and Mode of Action studies.
We offer fast turnaround times on well-designed, executed and reported studies. This allows you to efficiently integrate studies in your pre-clinical product development. Other advantages are flexibility, case-by-case designs, and a cost-efficient conduct of studies in compliance with GLP principles.